Patient Outcomes

Abstract

Abstract

CONTEXT AND OBJECTIVE:

Anemia and blood transfusions are common in intensive care. This study aimed to evaluate epidemiology and outcomes among critically ill patients under a restrictive transfusion strategy.

DESIGN AND SETTING:

Prospective observational cohort study in an intensive care unit (ICU) at a tertiary hospital.

METHODS:

Abstract

BACKGROUND:

Several prognostic factors for patients who have undergone esophagectomy owing to esophageal squamous cell carcinoma have been suggested, including intraoperative blood loss. There are few data, however, suggesting such an association with the prognosis following radical esophagectomy.

METHODS:

Summary Morbidity and Mortality Risk Associated with Red Blood Cell and Blood-component Transfusion in Isolated Coronary Artery Bypass Grafting

Summary Transfusion in Coronary Artery Bypass Grafting is Associated with Reduced Long-Term Survival

Koch CG, Li L, Duncan AI, Mihaljevic T, Loop FD, Starr NJ, Blackstone EH. Ann Thorac Surg. 2006 May;81(5):1650-7.
Department of Cardiothoracic Anesthesia, The Cleveland Clinic Foundation, Cleveland, Ohio
Abstract Here

Summary Given burn injury patients were not analyzed in the TRICC (Hebert PC et al) and CRIT (Corwin HL et al) studies and the limited applicability of these studies to this patient group, 21 burn centers (centers participating in

Summary This is another study in a series by the cardiac surgery team at the Cleveland Clinic Foundation investigating the association between red blood cell (RBC) and platelet transfusions and adverse patient outcomes. From a cohort of 12,536 patients undergoing cardiac surgery (coronary artery bypass grafting [CABG], valve repair or replacement, and combined CABG and valve surgery) 7,321 who completed a self-administered functional quality-of-life survey pre- and postoperatively were examined. Data was collected prospectively and concurrently with patient care.

Summary Dr Blajchman presents a comprehensive review of the available evidence for leukoreduction reducing the adverse events associated with the transfusion of allogeneic blood products. He divides the reputed clinical benefits of leukoreduction into three categories, 1) those that are proven to be clinically relevant, 2) those likely to be clinically relevant, and 3) those that are of unproven or theoretical benefit.

Summary In this retrospective single-center study Basran and colleagues demonstrate an association between red blood cell (RBC) storage time and increased short and long-term mortality, postoperative acute renal dysfunction (ARD) and increased intensive care unit (ICU) and hospital length of stay (LOS) in patients undergoing repeat cardiac surgery. 321 patients met their study criteria, which included patients undergoing repeat median sternotomy for coronary artery bypass graft or valve replacement surgery on cardiopulmonary bypass and who received allogeneic RBCs.

Summary In a retrospective observational study published in 2002 Taylor and colleagues reported an association between red blood cell (RBC) transfusion and increased nosocomial infection (NI) and worse outcomes in critically ill patients. The authors believe this current prospective observational cohort study provides stronger evidence for an association between RBC transfusion and NI and increased mortality and hospital and ICU length of stay (LOS). 2,085 surgical and medical ICU patients admitted to a single center were enrolled in the study.