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Acute Normovolemic Hemodilution (ANH)


Acute normovolemic hemodilution (ANH) is a blood conservation modality used in the operating room by anesthesiologists. Whole blood is drained by gravity into blood collection bags containing anticoagulant. As blood is collected, asanguinous fluid, either colloid and/or crystalloid, is infused to maintain hemodynamic stability and "normovolemia." This process tends to dilute the patients blood, hence the term "hemodilution." On completion of the surgical procedure, the patient's whole blood is retransfused. Other terms used are acute isovolemic hemodilution and intraoperative autologous donation (IAD). ANH creates a personalized blood bank for patients, since fresh whole blood contains red blood cells, coagulation factors and platelets.